Printable microfluidic systems using pressure sensitive adhesive material for biosensing devices

Wang, X., Nilsson, D., Norberg, P.
Type of publication: 
Journal article

In biosensors with a fluid analyte, the integration of a microfluidic system, which guides the analyte
into the sensing area, is critical. Quicker and economical ways to build up microfluidic systems will
make point of care diagnostics viable. Printing is a low-cost technology that is increasingly used in emerging
organic and flexible electronics and biosensors. In this paper, we present printed fluidic systems on flexible
substrates made with pressure sensitive adhesive materials.
Methods: Printable pressure sensitive adhesive materials have been used for making microfluidic systems.
Flexible substrates have been used, and two types of adhesive materials, one thermally dried and another
UV curable, have been tested. Top sealing layer was laminated directly on top of the printed microfluidic
structure. Flow tests were done with deionized water.
Results: Flow tests with deionized water show that both adhesive materials are suitable for capillary flow
driven fluidic devices. Flow test using water as dielectric material was also done successfully on a printed
electrolyte gated organic field effect transistor with an integrated microfluidic system.
General significance: Due to its ease of process and low cost, printed microfluidic system is believed to
find more applications in biosensing devices. This article is part of a Special Issue entitled Organic
Bioelectronics—Novel Applications in Biomedicine.

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Published in: 
Biochimica et Biophysica Acta, vol. 1830, pp. 4398-4401